Big Pharma and the Big Lie – The Chemical Imbalance Theory of Mental Illness
- Marcus Nikos
- Apr 6, 2025
- 14 min read

Big
Pharma is one of the largest and most
profitable businesses in America and in
order to sell their chemical Goods to
allegedly treat the Mind psyche
pharmaceutical companies must convince
society that people's mental and
behavioral problems are caused by the
bodily
chemicals an epidemic of mental illness
has spread across the modern world
according to the National Institute for
mental health 25% of All American adults
suffer from at least one mental illness
as do 15% of all children many in the
field of Psychiatry claim that
psychiatric drugs are the most effective
tool we have to counter this epidemic
and as a result these drugs are heavily
prescribed in the Western World in the
series of videos we explore the lies and
propaganda that are used to justify the
use of psychiatric drugs and we expose
the Deep corruption that exists at the
heart of the Unholy Alliance of modern
Psychiatry and big Pharma in this first
video we expose the big lie that
supports the millions of psychiatric
drug prescriptions written each year and
the billions of dollars of profits that
pharmaceutical companies earn from their
sales this lie is that chemical or
neurotransmitter imbalances are a
primary cause of mental illness and that
taking psychiatric drugs corrects for
these
imbalances if a lie is only printed
often enough it becomes a quasi truth
and if such a truth is repeated often
enough it becomes an article of belief a
Dogma in the late 19th century
Psychiatry suffered low status among the
medical professions there were few
generally agreed upon treatments for
mental illness and while medical doctors
were rapidly improving their capacity to
understand and treat the disorders of
the body Psychiatry was relatively
stagnant with respect to understanding
the disorders of the Mind the fate of
Psychiatry changed however when the
German psychiatrist Amil kraan put forth
a bold and revolutionary theory kraan
hypothesized that mental disorders such
as depression anxiety and schizophrenia
are the result of underlying physical
pathologies in the brain and body klan's
Theory caught on like wildfire as it
aligned with materialism the dominant
scientific Paradigm at the time
materialism is a philosophical position
which claims that matter is the primary
Sole and fundamental element of reality
and that our mind is an emergent
property of and reducible to the
interaction of material parts of our
brain in aligning Psychiatry with the
materialist position and hence the
scient ific community at large crain's
Theory radically improved the status of
Psychiatry crappin became the founder of
modern Psychiatry and the widespread
acceptance of his theory ushered in a
wave of experimental psychiatric
treatments targeting the brain and
bodily malfunctions believed to underly
mental illness in his book cracked why
Psychiatry is doing more harm than good
James Davies writes in the 1920s these
treatments included surgically removing
parts of the patient body their teeth
tonsils colons spleens and uteri
injecting patients with horse serum
using carbon dioxide to induce
convulsions and Comas injecting patients
with Cyanide and giving them hypothermia
another treatment was malaria therapy
injecting the patient with the malaria
parasite in the hope that the high
temperatures malaria produced would kill
the virus then thought responsible for
mental disease many patients failed to
recover from the Aria
disease the ineffectiveness of these
early 20th century treatments did not
stop psychiatrists from developing new
experimental treatments in the 1930s
insulin shock therapy was invented which
involved giving patients high doses of
insulin that would trigger intense
seizures and place the patient in a coma
Davies writes that after this procedure
granted patients would appear to feel
calmer but they would often show memory
loss and other neurological
abnormalities such as loss of speech 5%
of all patients actually died from this
treatment in the 1940s labotomy or the
surgical removal of parts of the brain
thought to be responsible for mental
disorders was invented and by the 1970s
1 million people in the United States
had been lobotomized another treatment
which grew in popularity in the 1940s
was electroconvulsive therapy or ECT
which involved administering electric
shocks to the brain of a depressed
patient in order to induce severe
seizures in the words of Davies all
these outlandish and barbaric treatments
one impetus and legitimacy from
psychiatry's enduring conviction that
there must be a physical basis for
mental disorder this originated with
crain's assumption if our emotional
maladies are biologically caused then
the body is where our efforts must be
directed after half a century of
experimenting with psychiatric
treatments that not only proved
ineffective but often harmed handicapped
or killed patients the field of
Psychiatry faced a Crisis general
medicine was advancing via revolutionary
breakthroughs such as the first organ
transplants and blood transfusions as
well as the discovery of antibiotics and
Insulin psychiatry in contrast had found
little success within the materialist
Paradigm that dominated scientific
discourse this all changed in the 1950 s
with the development of the first
generation of psychiatric drugs prior to
the 1950s sedatives and stimulants were
commonly prescribed in psychiatric
institutions to subdue and control a
psychotic or heavily depressed patient
however psychiatrists were not publicly
open regarding how they were using these
drugs official reticence about the old
drugs conveys the impression that they
were a source of embarrassment writes
the British psychiatrist Joanna monrie
however in the 1950s after a new
collection of psychiatric drugs were
discovered psychiatrists started to
publicly Embrace their use
chlorpromazine the first neuroleptic or
antis psychotic which was marketed under
the name of Thorazine was discovered
when researchers searching for
antimalarial drugs discovered that
chlorpromazine functioned as a major
tranquilizer which induced in patients a
euphoric quietude patients are calm
andom
with a relaxed and detached expression
the first anxiolytic or anti-anxiety
drug was a minor tranquilizer which was
discovered by researchers searching for
a drug to treat gram negative microbes
while the first anti-depressant was a
psychological stimulant that was
discovered by researchers searching for
a drug treatment for
tuberculosis these discoveries initiated
what is called the psychopharmacological
Revolution and in the words of monrie
these drugs were greeted with immense
enthusiasm verging on Zeal one
contemporary Observer noted that the
atmosphere at conferences on the new
drugs was akin to religious revivalist
meetings from this time on textbooks
started to cover drug treatments in
detail and proclaimed their
transformative effects pharmaceutical
companies realized that psychiatric
drugs could be marketed and sold not
only to institutionalized patients but
to the general public and so they began
investing heavily in the research and
development of psychiatric drugs in 1955
Wallace Laboratories brought mobam mate
to the market selling it under the name
miltown and marketing it as a minor
tranquilizer that could ease anxiety and
worry following an extensive marketing
campaign demand for miltown soared the
public rush to obtain this new drug was
such that Wallace Laboratories and
Carter products which were jointly
selling mobam mate struggled to keep up
with the demand following the success of
miltown in 1963 the drug maker Hoffman
lar Ro brought Valium the first benzo
dipene to Market Valium was marketed
primarily to anxious Housewives and from
1965 to 1981 it was the bestselling drug
in the West in the theme of the Rolling
Stone song Mother's Little Helper in
1967 one in three American adults filled
a prescription for a psychoactive
medication with a total sales of such
drugs reaching $692 million wrote Robert
Whitaker this first generation of
psychiatric drugs were not only highly
profitable for pharmaceutical companies
they also granted the field of
Psychiatry the status and legitimacy it
had long been seeking for as Joanna
monrie writes these first generation
drugs were an intervention on the body
and as drug treatment grew in importance
in other areas of medicine they
confirmed the desired parallels between
Psychiatry and Physical
Medicine the success these drugs
conferred on Psychiatry and
pharmaceutical companies was shortlived
as the public soon became aware that
consuming these drugs produced negative
side effects while Hoffman larash
claimed that Valium provided pure
Anxiety Relief and was safe harmless and
non-addicting many users reported
physical dependence terrible withdrawal
effects as well as insomnia panic
attacks and heightened levels of anxiety
in 1975 the US justice department
classified benzodiazapines as schedule
for drugs under the control substance
act prescriptions for Valium as well as
other psychiatric drugs plummeted and a
growing public awareness of the harmful
nature of psychiatric drugs led to the
development of an anti Psychiatry
movement the intellectual father of the
anti Psychiatry movement Thomas sass
argued that psychiatrists were agents of
social control and that the diagnosis
and medication of the mentally ill was a
way to subdue individuals who are
reacting in an undesirable manner to
life in a sick and oppressive Society in
1975 sas's idea found legitimacy when a
highly publicized government
investigation into the use of
neuroleptics in juvenile institutions
was hijacked by ex-patients who
testified that the drugs caused
excruciating pain and turned them into
emotional zombies one patient said that
such drugs are used not to heal or help
but to torture and control it is that
simple this anti Psychiatry movement
reached popular Consciousness via the
Oscar winning movie One Flew Over the
Cuckoo's Nest which portrayed Mental
Hospitals as facilities of torture and
control the anti- Psychiatry movement as
well as the drop in the sales of
psychiatric drugs led the director of
the American Psychiatric association
Melvin sapin to state in 1980 that the
profession is under severe Siege a
solution was needed to save Psychiatry
as well as the profits of pharmaceutical
companies and a solution was found
pharmaceutical scientists gave Amil
klan's Theory a modern spin they claimed
that mental illness is caused by
neurotransmitter imbalances in the brain
and that psychiatric drugs correct for
such imbalances fix a broken brain and
cure mental disorders this idea became
known as the chemical imbalance Theory
the of mental illness regarding the
researcher Who is credited with
popularizing this Theory James Davies
writes in the early 1960s a young
medical researcher stumbled upon an idea
that would launch a paradigm shift in
Psychiatry the researcher was called
Joseph schildkraut and the idea he
advanced was rather simple fluctuations
in our moods may be due to chemical
imbalances in our brains to be sure
schildkraut was not the first person to
entertain this compelling idea
it had been floating around the
psychiatric community in one form or
another since the mid1 1950s when the
first anti-depressants started to be
used but for some reason when
schildkraut published his hypothesis in
the American Journal of psychiatry in
1965 his views took the community by
storm although schildkraut admitted his
theory was at best a reductionist
simplification that could neither be
rejected nor confirmed on the basis of
data currently available pharmaceutical
scientists and psychiatrists ran with
this Theory and started to act as if it
were true not only for depression but
for all mental disorders yet as they
lacked hard evidence to support it the
chemical imbalance theory of mental
disorders was Advanced through a line of
reasoning that is illogic unscientific
and bordering on absurd for example with
respect to depression pharmaceutical
scientists identified how drugs to treat
depression increased levels of norpine
and serotonin in the brain and thus they
claimed that depression is caused by low
levels of norepinephrine and serotonin
similarly they noticed that neuroleptics
or antis psychotics decreased dopamine
Transmission in the brain and hence they
proposed that schizophrenia is due to
excessive levels of dopamine or as
Robert Whitaker explains this became the
storytelling formula that was relied
upon by pharmaceutical companies again
and again researchers would identify the
mechanism of action for a class of drugs
how the drugs either lowered or raised
levels of a brain neurotransmitter and
soon the public would be told that
people treated with those medications
suffered from the opposite problem the
following passage by the psychiatrist
Robert Taylor hammers home just how
absurd and pseudoscientific this line of
reasoning is in the absence of any real
progress and psycho pharmacology psycho
drug makers have relied on marketing
gimmicks by far the most successful one
portrays psycho drugs as treatment for
specific chemical imbalances in the
brain since psycho drugs alter brain
chemicals so the pitch goes the
conditions they target must be caused by
chemical imbalances a similar line of
illogical reasoning would have us
believe that aspirin deficiency causes
headache since when we take aspirin the
headache gets better or as Joanna monrie
explains regarding the chemical
imbalance theory of mental disorders
that took off in the 1970s
the drug companies were trying to
capture that huge Market of people who
once took tranquilizers but because the
old model of how drugs work had been
tarish they needed a new model to
reassert their value and necessity so
now these drugs were cast as curing us
rather than changing us and that's where
the idea of the chemical imbalance came
in it was perfect because it implied
that these drugs actually corrected a
defect in the brain if you have a brain
disorder a chemical imbalance in this is
going to correct that imbalance then
obviously you must take it and this
unthinking acceptance of the disease
centered view has dominated mainstream
Psychiatry for the last 20 or 30 years
to convince the public of the chemical
imbalance theory of mental disorders one
of the biggest propaganda campaigns in
history was conducted the major parties
involved included the American
Psychiatric association or APA big
Pharma the nonprofit organization
National Alliance on Mental Illness or
nmi as well as the National Institute of
Mental Health or n or as Robert Whitaker
writes a powerful quartet of voices came
together during the 1980s eager to
inform the public that mental disorders
were brain diseases pharmaceutical
companies provided the Financial Muscle
the APA and psychiatrists at top medical
schools conferred intellectual
legitimacy upon the Enterprise the NIMH
put the government's stamp of approval
on the story n Ami provided a moral
Authority this was a coalition that
could convince American Society of
almost
anything this propaganda campaign
initially focused on convincing the
public that depression is caused by a
chemical imbalance Depression was likely
chosen as the initial Target of this
campaign because of the fact that most
people experiened depression at some
point in life and so a massive Market
exists for drugs promoted as
anti-depressant in 1984 the NIMH
launched an educational program called
depression awareness recognition and
treatment or Dart whose stated purpose
was to change public attitudes so that
there is greater acceptance of
depression as a disorder rather than a
weakness the NIMH director Lewis Jud in
1990 unequivocally claimed two decades
of research have shown that psychiatric
disorders are diseases and illnesses
like any other diseases and illnesses
newspapers magazines and books by
renowned psychiatrists were also used in
this propaganda campaign in 1989 New
York Magazine placed the anti-depressant
drug Prozac on its cover with the
headline bye-bye Blues a new wonder drug
for depression one year later Newsweek
magazines cover read Prozac a
breakthrough for depression in the same
year one of America's most famous
science writers at the time Natalie
Angier of the New York Times wrote wrote
that anti-depressants work by restoring
the balance of neurotransmitter activity
in the brain correcting an abnormal
excess or inhibition of the
electrochemical signals that control
mood thoughts appetite pain and other
Sensations in 1993 the Brown University
psychiatrist Peter Kramer published the
book listening to Prozac which spent 21
weeks on the New York Times bestseller
list and in which he stated that Prozac
was making some patients better than
well and ushering in a new era of
cosmetic
psychopharmacology the United States was
not the only country to spread big
farmers propaganda the Royal colleges of
psychiatrists in the UK set up a defeat
depression Campaign which was funded by
the pharmaceutical company Eli Lily the
makers of proac the campaign in the
words of monrie sought to persuade
General Practitioners that they should
diagnose more people as depressed and
prescribe more anti-depressants the
campaign also aimed to reduce the
general Public's resistance to taking
drugs for depression in both the UK and
America these propaganda campaigns were
enormously successful this selling of
depression which was being done under
the guise of a public education campaign
turned into one of the most effective
marketing efforts ever devised writes
Robert Whitaker between 1992 and 2002
the number of prescriptions issued for
anti-depressants in the UK increased by
2
235% in 1992 sales of Prozac in the
United States reached $1 billion
pharmaceutical companies were swimming
in profits impatients flocked to
psychiatrists to be told which chemical
imbalance was responsible for their
mental distress and which drugs would
fix their brain the widespread
acceptance of the chemical imbalance
Theory gave the field of Psychiatry the
legitimacy it was looking for for as the
psychiatrist David Healey explained it
set the stage for psychiatrists to
become real doctors or as Robert
Whitaker writes doctors in Internal
Medicine had their antibiotics and now
psychiatrists could have their anti-d
disease pills too the problem with this
public relations campaign is that the
chemical imbalanced theory that was sold
to the public is false it is a big lie
many Professionals in the public have
been falsely convinced that biochemical
imbalances in the brain Drive mental
suffering such as the serotonin theory
of depression or the dopamine theory of
so-call schizophrenia yet the evidence
for any biological basis for psychiatric
disorders is utterly lacking or as the
psychiatrist Joanna monrie echoes in the
introduction to the myth of the chemical
cure this book exposes the traditional
view that psychiatric drugs Target
underlying diseases or correct chemical
imbalances as fraud it traces the
emergence of this View and suggests that
it was adopted not because there was any
evidence to support it but because it
served the vested interest of the
psychiatric profession the
pharmaceutical industry in the modern
State you're watching the first video in
our four-part series on the Corruptions
of Psychiatry and the big lies of big
Pharma the entire series is available
exclusively to our supporting members to
access it and over 100 other membership
videos join our membership program at
academyof ideas.com members you can
cancel your membership at any time some
stud ities funded by the pharmaceutical
industry have concluded that low
serotonin levels are implicated in
depression which seems to suggest that
drugs to raise these levels May improve
depressive symptoms but the methodology
of these studies has been revealed as
highly flawed monre notes that
contradictory evidence has been
overlooked or reframed as supportive
follow-up Studies have found no
connection between serotonin levels in
depression and metaanalyses Of Studies
have further dispelled the myth that
serot tonin is implicated in depression
and as Johan Hari explains if depression
and anxiety are caused by a chemical
imbalance and anti-depressants work by
fixing that imbalance then you have to
account for something odd that
scientists kept finding anti-depressant
drugs that increase serotonin in the
brain have the same modest effect in
clinical trials as drugs that reduce
serotonin in the brain and they have the
same effect as drugs that increase
another chemical norpine
and they have the same effect as drugs
that increase another chemical dopamine
in other words no matter what chemical
you Tinker with you get the same outcome
or as nir gamy a psychiatrist and
neuroscientist at novaris Institute one
of the largest pharmaceutical companies
in the world explains our bestselling
psychopharmacology textbook consists of
pure speculations presented as pretty
pictures which we mistake for science we
have a huge amount of neurobiology
research now to conclude that
neurotransmitter theories of
psychopharmacology basically are false
the dopamine and serotonin hypotheses of
schizophrenia and depression are wrong
one of the problems with studies that
seek to prove the chemical imbalance
theory of mental illness is that we
possess no real understanding of how
neurotransmitter levels influence or
impact Human Experience furthermore
neurotransmitter levels in the brain are
constantly fluctuating and there is no
agreed upon standard of what constant
healthy levels as there is no known
normal balance of neurotransmitters
there is no way to know what an
imbalance would look like and no way to
test if a brain is chemically imbalanced
or as the professor of Psychiatry at
Northwestern University Hospital David
Kaiser writes patients have been
diagnosed with chemical imbalances
despite the fact that no test exists to
support such a claim and there is no
real conception of what a correct
balance would look like yet conclusions
such as depression as a biochemical
imbalance are created out of nothing
more than semantics and The Wishful
Thinking of scientists and psychiatrists
and a public that will believe anything
now that has the stamp of approval of
Medical
Science while the chemical imbalanced
theory of mental disorders is what the
professor amortis of Psychiatry Ronald
pies called an urban legend this Theory
continues to be widely promoted as an
Undisputed Truth by the psychiatric
industry big Pharma government agencies
in the main mream media for example in
2005 the American Psychiatric
association stated that anti-depressants
may be prescribed to correct imbalances
in the levels of chemicals in the brain
while in 2019 Shannon hodj a
correspondent for CNN which receives
millions of dollars each month in
advertising for big Pharma stated that
researchers identified the chemical
imbalances that correlate with problems
such as depression and Ed treatments
such as Prozac or Zoloft which block the
reabsorption of Serotonin so more of it
can remain floating around in the brain
the more serotonin floating around the
happier we feel in an article titled
psychiatry's incurable hubris the
psychotherapist Gary Greenberg notes how
the widespread acceptance of the
chemical imbalance theory of mental
disorders has been an act of mass
deception perpetuated on an unsuspecting
public the chemical imbalance Theory May
Fail as science but as rhetoric it has
turned out to be a wild success or as
Joanna monrie Echoes it appears that
recent propaganda has been effective
enough to persuade a large section of
the population that their biochemistry
is aai and that they need drug treatment
to correct it but if the chemical
imbalance theory of mental disorders is
a big lie and there is no known
neurotransmitter imbalances for
psychiatric drugs to fix then what are
psychiatric drugs doing to the brain and
mind


