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A synthetic cure for obesity…

  • Writer: Marcus Nikos
    Marcus Nikos
  • Feb 9
  • 2 min read

A synthetic cure for obesity…


Eli Lilly just released absolutely incredible data from a Phase 3 clinical trial of its obesity drug. It’s called tirzepatide. And it appears this drug can help people lose weight effortlessly.

The Phase 3 trial of tirzepatide included over 2,500 patients across nine different countries. The average weight of clinical trial participants was roughly 250 pounds. Each was given weekly injections of the drug in varying doses over 72 weeks.

And the results were phenomenal.

The patients experienced an average weight loss of about 52 pounds. In percentage terms, they reduced their body weight by an average of 22.5%.

That’s transformational. We’re talking about the difference between being pre-diabetic with comorbidities and then having a healthy body-mass index (BMI).

And here’s the kicker – the patients didn’t have to change anything about their lifestyle at all. All that happened is that they no longer felt the desire to consume the same number of calories as before.

That’s because tirzepatide contains synthetic versions of two key hormones – GLP-1 and GIP. Our bodies release these hormones after a meal to make us feel full.

By maintaining a schedule of weekly tirzepatide injections, patients simply didn’t feel the need to eat or drink nearly as much… That’s how they lost so much weight.

So I see this as one of the most exciting drugs in Phase 3 clinical trials today.

For context, over 42% of people in the U.S. are considered to be clinically obese today. That’s nearly half the population. I was actually one of those people back in 2020 when I found out that I was pre-diabetic.

It took me a year of exercise and training and radical changes to my consumption to return back to a healthy weight. It had a transformational impact on my health, energy, and immune system. But it was difficult, painful, and even uncomfortable at times.

Still, I’d do it again. But what if there was a way to affect the same change and have some help in doing so? How many people would jump at the chance to lose 22.5% of their weight just by taking shots each week?

What’s more, tirzepatide provides similar benefits to bariatric surgery… except with no invasive surgical procedure necessary. That makes this drug a no-brainer for anyone considering therapeutic approaches to weight loss.

This is a blockbuster in the making. I’ll be watching the remainder of the clinical trial closely.

 
 
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